Identification of proinsulin and C-peptide in human serum by a specific immunoassay.
نویسندگان
چکیده
An immunoassay for the measurement of human proinsulin and C-peptide is described. By a combination of this system and an insulin immunoassay, proinsulin, insulin, and C-peptide were identified in acid-ethanol extracts of serum after gel filtration. In keeping with the results of biosynthetic studies, insulin and C-peptide were found to be present in equimolar amounts. The absolute values of serum proinsulin determined independently in the two assays corresponded closely.
منابع مشابه
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 67 1 شماره
صفحات -
تاریخ انتشار 1970